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They ran four parallel studies based on different patient profiles: ADM trial: Patients with type 2 diabetes (T2D), comparing newer GLP-1 RAs to older GLP-1 RAs, sulfonylureas, and other anti-diabetic medications (ADMs)
Once-weekly preparations such as dulaglutide and extended-release exenatide produce more stable plasma concentrations with fewer peak-to-trough fluctuations compared with daily or twice-daily formulations
Rotating injection sites helps prevent lipodystrophy, where repeated injections in the same area cause changes in the fat tissue
These drugs are very effective at reducing blood sugar and when one rapidly reduces blood sugar it can cause swelling in the optic nerve, Katz explained
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